Comparative in vitro-in vivo correlation analysis with pioglitazone tablets

نویسندگان

  • Sajal Kumar Saha
  • A. K
  • Azad Chowdhury
  • Sitesh Chandra Bachar
  • Sreedam Chandra Das
  • Ruhul H. Kuddus
  • Md Aftab Uddin
چکیده

Sajal Kumar Saha*, A. K. Azad Chowdhury, Sitesh Chandra Bachar, Sreedam Chandra Das, Ruhul H. Kuddus, Md Aftab Uddin Department of Clinical Pharmacy and Pharmacology, University of Dhaka, Dhaka-1000, Bangladesh Department of Pharmaceutical Technology, University of Dhaka, Dhaka-1000, Bangladesh Department of Genetic Engineering and Biotechnology, University of Dhaka, Dhaka-1000, Bangladesh Asian Pac J Trop Dis 2013; 3(6): 487-491

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Design and Comparative Evaluation of In-vitro Drug Release, Pharmacokinetics and Gamma Scintigraphic Analysis of Controlled Release Tablets Using Novel pH Sensitive Starch and Modified Starchacrylate Graft Copolymer Matrices

The present investigation deals with the development of controlled release tablets of salbutamol sulphate using graft copolymers (St-g-PMMA and Ast-g-PMMA) of starch and acetylated starch. Drug excipient compatibility was spectroscopically analyzed via FT-IR, which confirmed no interaction between drug and other excipients. Formulations were evaluated for physical characteristics like hardness,...

متن کامل

Design and Comparative Evaluation of In-vitro Drug Release, Pharmacokinetics and Gamma Scintigraphic Analysis of Controlled Release Tablets Using Novel pH Sensitive Starch and Modified Starchacrylate Graft Copolymer Matrices

The present investigation deals with the development of controlled release tablets of salbutamol sulphate using graft copolymers (St-g-PMMA and Ast-g-PMMA) of starch and acetylated starch. Drug excipient compatibility was spectroscopically analyzed via FT-IR, which confirmed no interaction between drug and other excipients. Formulations were evaluated for physical characteristics like hardness,...

متن کامل

Formulation Development, Characterization and Evaluation of Liquisolid Tablet Containing Pioglitazone Hcl

The aim of present study was to improve the solubility of pioglitazone HCl a practically insoluble antidiabetic drug by using liquisolid technique. The in vitro release pattern of liquisolid tablets and directly compressed tablets were studied using USP-II apparatus. Different Liquisolid tablets were prepared using a mathematical model to calculate the required quantities of powder and liquid i...

متن کامل

Pharmacokinetics and Pharmacodynamics of Gliclazide from Immediate and Modified Release Formulation Tablets in Rats

The objective of the study was to compare pharmacokinetic and pharmacodynamic parameters of gliclazide after administration of immediate (IR) and modified release (MR) tablets. The experiment included rats with both normoglyceamia and streptozocin (STZ)-induced hyperglyceamia. Several MR formulations were designed and in vitro drug release profile was assessed by a dissolution test. For the fur...

متن کامل

Pharmacokinetics and Pharmacodynamics of Gliclazide from Immediate and Modified Release Formulation Tablets in Rats

The objective of the study was to compare pharmacokinetic and pharmacodynamic parameters of gliclazide after administration of immediate (IR) and modified release (MR) tablets. The experiment included rats with both normoglyceamia and streptozocin (STZ)-induced hyperglyceamia. Several MR formulations were designed and in vitro drug release profile was assessed by a dissolution test. For the fur...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2013